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In addition, a consolidated overview of the biological effects of PYC, categorized by study type and quality of evidence, is provided in Table 2
Patients who underwent randomization were treated with at least one dose of study medication, and had available post-baseline data on exacerbation were included in the FAS for exacerbation, and those who had available spirometry data at 12 months or 24 months were included in the FAS for lung function
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